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BlephaDerm®

Trehalose • Hyaluronic Acid • Ophiopogon Japonicus

Where Eyelid Care Meets Skin Care

Soothing eyelid and eye contour cream for hydrating, protecting and repairing the delicate eyelid skin that supports ocular health.

BlephaDerm® at a Glance:
A Unique* Complex for
Eyelid Skin

Synergy from natural ingredients1

  • Trehalose provides bioprotection2 and regenerates skin moisture barrier3,4
  • Hyaluronic Acid provides hydration5 and offers immediate comfort5
  • Ophiopogon Japonicus targets itchy and inflamed skin6, soothes and repairs dry skin6,7, and supports your eyelid microbiota7
  • With 9 additional ingredients and water

The first* preservative-free eyelid cream that soothes, protects and repairs7

  • Soothes by providing relief from itching7
  • Protects by enhancing the skin moisture barrier and natural defenses7
  • Repairs and moisturizes with immediate and long-lasting hydration and comfort7

* Innovative Trio of Natural Ingredients.

How to Use BlephaDerm®

Apply twice a day, morning and evening, on cleansed skin1

1. Gently smooth from the inner corner of your eye to the outer corner.

2. Gently dab onto your eyelid from the inner corner to the outer corner. 

Why Take Care of Your Eyelids?

Eyelid skin is unique8

1. Protect your eyes from external environment

2. Facilitate the lubrication of your eyes

3. Spread the tears on your ocular surface

Common Risk Factors Can Impact Delicate Eyelid Skin9,10

Signs and Symptoms of Damaged Eyelid Skin

Itching, redness, and irritation11

Crusting11

Dryness and burning11

Under-eye puffiness and dark under-eye circles10,11,12

Taking Care of Your Eyelids

How can we support your unique eyelid skin and a healthy eyelid microbiome?

With formulas that are:

  • Preservative-free, perfume-free and sterile
  • Minimalist, and made with only essential ingredients
  • Designed with ingredients that support your eyelid microbiota

A Healthy and Balanced Eyelid Microbiome Ensures Healthy Eyelid Skin12

  • Millions of bacteria, fungi and viruses are living on the eyelids13
  • A balanced microbiome contributes to the barrier function of the skin13
  • Each person’s microbiome is unique14

Patient Preferred15,16

In ophthalmological and dermatological clinical studies, BlephaDerm® provided significant improvements in patient reported:

  • 77% of patients reported under-eye puffiness was decreased after 28 days16
  • 86% of patients reported significantly improved skin uniformity and eye contour skin colour15

Clinically Proven16,17

In ophthalmological and dermatological clinical studies, BlephaDerm® provided significant improvements in:

  • Moisturizing effect was still significantly increased after 8 hours17
  • After 28 days of use:
    • Irritation was immediately reduced at 10 minutes, with a 95% reduction
    • Itching was significantly reduced at 10 minutes, with a 94% reduction
    • Discomfort was immediately reduced at 10 minutes, with a 92% reduction

The Théa Daily Routine for Eyelids

Reusable warming eye mask for the treatment of MGD and blepharitis, specifically designed to provide rapid relief and long-lasting ocular comfort.

+

The only daily lid hygiene wipe with clinically proven antimicrobial properties18 Indicated for blepharitis, MGD, styes, chalazion, baby eye infections, conjunctivitis, pre- and post-ocular surgery, complementary treatment with demodex treatment.

OR

Soothing and cooling gel for daily lid hygiene of sensitive eyelids and eyelashes.
It provides a refreshing sensation, soothes the eyelids and removes impurities.

+

Soothing eyelid and eye contour cream for hydrating, protecting and repairing sensitive skin.

Where to Buy

Inquire about BlephaDerm®

† Meibomian Gland Dysfunction

References:
1. BlephaDerm® Product Leaflet. Thea Pharma Inc. 2. Jain NK, Roy I. Effect of trehalose on protein structure. Protein Sci. 2009;8(1):24-36. 3. Čejkova J, et. al. Trehalose treatment accelerates the healing of UVB-irradiated corneas. Comparative immunohistochemical studies on corneal cryostatsections and corneal impression cytology. Histol Histopathol. 2012;27(8):1029- 1040. 4. Li J, Robieux C, et. al. Therapeutic efficacy of trehalose eye drops for treatment of murine dry eye induced by an intelligently controlled environmental system. Mol Vis. 2012;18:317-329. 5. Juncan AM, et. al. Advantages of hyaluronic acid and its combination with other bioactive ingredients in cosmeceuticals. Molecules. 2021;26(15):4429. 6. Mainzer C, et. al. Clinical efficacy of oligofructans from Ophiopogon japonicus in reducing atopic dermatitis flare-ups in Caucasian patients. Acta Derm Venereol. 2019;99(10):858-864. 7. Messaraa C, et. al. Can performance and gentleness be reconciled? A skin care approach for sensitive skin. Cosmetics. 2022;9(2):34. 8. Pratchyapruit W, et. al. Functional analyses of the eyelid skin constituting the most soft and smooth area on the face: contribution of its remarkably large superficial corneocytes to effective water-holding capacity of the stratum corneum. Skin Res Technol. 2007;13(2):169-175. 9. Craig JP, et al. TFOS DEWS II Definition and Classification Report. The Ocular Surface. 2017;15:276-283. 10. Sullivan DA, et al. TFOS Lifestyle: Impact of cosmetics on the ocular surface. Ocul Surf. 2023;29:77-130. 11. Jourdan M, et al. Skin care management for medical aesthetic procedures to prevent scarring. Clin Cosmet Investig Dermatol. 2019;12:799-804. 12. Johnson JL. The human skin microbiome and its changes in atopic dermatitis. September 28, 2022. Accessed October 29, 2023. https://nationaleczema.org/blog/microbiome-and-atopic-dermatitis/ 13. Aragona P, et al. The ocular microbiome and microbiota and their effects on ocular surface pathophysiology and disorders. Surv Ophthalmol. 2021;66(6):907-925. 14. Carvalho MJ, et. al. Skin microbiota and the cosmetic industry. Microb Ecol. 2023;86(1):86-96. 15. Data on file, Thea Pharma Inc. Clinical Study Report 182458: Clinical evaluation of the cutaneous and ocular acceptability and efficacy of a cosmetic product. Final report v1.0; January 18, 2019 16. Data on file, Thea Pharma Inc. Clinical Study Report 22E1350: Clinical evaluation of the cutaneous and ocular acceptability and efficacy of a cosmetic product in care of atopic skin. Final report v1.0; December 1, 2022. 17. Data on file, Théa Pharma Inc. Clinical Study Report 22E1351: Biometrological evaluation of the transepidermal water loss effect and a long-lasting moisturizing effect of a cosmetic product. Final report v1.0; July 5, 2022 18. Peral A, et al. Importance of lid hygiene before ocular surgery: qualitative and quantitative analysis of eyelid and conjunctiva microbiota. Eye Contact Lens. 2016;42(6):366-370.
BLEPHA-0224-002-E

Copyright ©2024 Théa Pharma Inc. All rights reserved. This information—including product information—is intended only for residents of Canada.
The products discussed herein may have different labeling in different countries. Site last updated: March 2024